The task force developed two frameworks to date, one for advanced disease and the other for potentially curative treatment. The frameworks are presented as scorecards, and as an example, the advanced disease framework considers overall survival likelihood or response rate (used to calculate a clinical benefit score) and toxicity scores. Bonus points are given for data supporting palliation of symptoms and treatment-free intervals. The net health benefit is then determined, and the regimen’s cost (eg, copay, drug acquisition cost) is then added. The scores are entered across the bottom of the framework, and these data can then be used to guide the physician–patient discussion about treatment options. The task force notes that the relative value of a specific cancer treatment is likely to change over time, and invites public comments until August 21, 2015 at www.asco.org/value.
Schnipper LE, Davidson NE, Wollins DS, et al. American Society of Clinical Oncology Statement: A conceptual framework to assess the value of cancer treatment options [published online before print June 22, 2015]. JCO. doi: 10.1200/JCO.2015.61.6706.