The Science of CRC is an advocacy program for patients with colorectal cancer. This program focuses on increasing global public awareness of colorectal cancer (CRC), the role of angiogenesis (new blood vessel growth) in CRC, and the importance of antiangiogenic treatments for patients with metastatic colorectal cancer (mCRC). The ScienceofCRC.org resource provides accurate, easy to understand, and useful information about the evidence supporting antiangiogenic therapy for mCRC. We believe everyone affected by mCRC can be empowered with knowledge of relevant treatments, and the practical steps they can take to fight cancer.