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A New Tumor Marker for Pancreatic Cancer?

Monday, July 24, 2017
Pancreatic cancer often is diagnosed at a later stage of disease. Ideally, identification of a tumor marker or other early detection technique would reduce deaths from pancreatic cancer.

Researchers at the Mayo Clinic and University of Pennsylvania identified secreted proteins and tested a subset of these proteins to determine if they might be markers of pancreatic ductal adenocarcinoma (PDAC). In a phase I study, a phase 2a validation study, and a second phase 2b study (746 blood samples in total), concentrations of plasma thrombospondin-2 (THBS2) were able to discriminate resectable stage I cancer as readily as stage III and IV pancreatic tumors. THBS2 plasma concentrations combined with those for CA 19-9 increased the ability to distinguish PDAC from pancreatitis, and may improve the early detection of PDAC.

The study findings are available at here.

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Lisa Schulmeister, MN, RN, ACNS-BC, FAAN
Blog Info
Lisa Schulmeister, MN, RN, ACNS-BC, FAAN is an oncology nursing consultant and editor-in-chief of Oncology Nursing News.
Author Bio
Lisa Schulmeister, MN, RN, ACNS-BC, FAAN, is the Editor-in-Chief for OncLive Nursing. She is an oncology nursing consultant and adjunct assistant professor of nursing at Louisiana State Health Sciences Center in New Orleans, LA. She provides continuing nursing education to nurses across the Unites States, is active in several professional nursing organizations, and is intrigued by the many ways nurses use technology to communicate.
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