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Pancreatic Cancer Risk Among People Newly Diagnosed with Diabetes

Monday, August 06, 2018
Lisa Schulmeister, MN, RN, FAAN
Lisa Schulmeister, MN, RN, FAAN
A group of US researchers led by Ayush Sharma, MD, from the Mayo Clinic in Rochester, Minnesota, developed and validated a model to determine the risk of pancreatic cancer in people newly diagnosed with diabetes. They analyzed data from four cohorts of people diagnosed with diabetes from 2000-2015 (n = 1,561). The newly created predictive model, which they named Enriching New-onset Diabetes for Pancreatic Cancer (END-PAC), weighed scores for the 3 factors most strongly associated with pancreatic cancer-change in weight, change in blood glucose level, and age at onset of diabetes.

An END-PAC score of 0 (in 49% of patients) correlated with an extremely low risk for pancreatic cancer. An END-PAC score >3 correlated with an increased risk of developing pancreatic cancer within 3 years.

The researchers concluded that significant weight loss, increased blood glucose levels, and older age at onset of diabetes may be useful in determining the risk of pancreatic cancer in people newly diagnosed with diabetes; however, further research is needed.

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Lisa Schulmeister, MN, RN, ACNS-BC, FAAN
Blog Info
Lisa Schulmeister, MN, RN, ACNS-BC, FAAN is an oncology nursing consultant and editor-in-chief of Oncology Nursing News.
Author Bio
Lisa Schulmeister, MN, RN, ACNS-BC, FAAN, is the Editor-in-Chief for OncLive Nursing. She is an oncology nursing consultant and adjunct assistant professor of nursing at Louisiana State Health Sciences Center in New Orleans, LA. She provides continuing nursing education to nurses across the Unites States, is active in several professional nursing organizations, and is intrigued by the many ways nurses use technology to communicate.
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