Join us for a LIVE, interactive broadcast on NSCLC Friday 10/5 – sign up today to be reminded to tune in!

Cancer-related Fatigue

Monday, November 26, 2012
The initial review of the effects of physical activity in reducing cancer-related fatigue, published in The Cochrane Library in 2008, identified some benefits of physical activity on fatigue during and after adjuvant treatment but also identified a number of study design limitations. To evaluate the current state of knowledge on the effect of exercise on cancer-related fatigue both during and after cancer treatment, researchers conducted a review of studies published on or before March 2011. Where data were available, the researchers performed meta-analyses for fatigue using a random-effects model. Fifty six studies (28 from the original search and 28 from the updated search) involving 4068 patients were reviewed. A meta-analysis of all fatigue data, incorporating 38 comparisons, provided data for 1461 patients who received an exercise intervention and 1187 control patients. At the end of the intervention period, exercise was significantly more effective than the control interventions. Benefits of exercise on fatigue were observed for interventions delivered during or post-adjuvant cancer therapy, and were identified for patients with breast and prostate cancer but not for those with hematological malignancies. Aerobic exercise significantly reduced fatigue but resistance training and alternative forms of exercise were not found to be statistically significant. These data were published online in The Cochrane Library on November 14, 2012.

The results of the Cochrane review are not all that surprising. Exercise, particularly aerobic exercise, is recognized as being energizing. Non-aerobic exercise, such as yoga and resistance weight training, did not significantly reduce fatigue; however, they may be beneficial in reducing other symptoms, such as anxiety. The research team concluded that further work is needed to determine the most effective exercise for fatigue management, including type, frequency, and duration. Tehere also is a need to develop and utilize consistent outcome measures.

Talk about this article with nurses and others in the oncology community in the General Discussions Oncology Nursing News discussion group.
Lisa Schulmeister, MN, RN, ACNS-BC, FAAN
Blog Info
Lisa Schulmeister, MN, RN, ACNS-BC, FAAN is an oncology nursing consultant and editor-in-chief of Oncology Nursing News.
Author Bio
Lisa Schulmeister, MN, RN, ACNS-BC, FAAN, is the Editor-in-Chief for OncLive Nursing. She is an oncology nursing consultant and adjunct assistant professor of nursing at Louisiana State Health Sciences Center in New Orleans, LA. She provides continuing nursing education to nurses across the Unites States, is active in several professional nursing organizations, and is intrigued by the many ways nurses use technology to communicate.
External Resources

MJH Associates
American Journal of Managed Care
MD Magazine
Pharmacy Times
Physicians' Education Resource
Specialty Pharmacy Times
OncNurse Resources

Continuing Education
Web Exclusives

About Us
Advisory Board
Contact Us
Privacy Policy
Terms & Conditions
Intellisphere, LLC
2 Clarke Drive
Suite 100
Cranbury, NJ 08512
P: 609-716-7777
F: 609-716-4747

Copyright OncNursing 2006-2018
Intellisphere, LLC. All Rights Reserved.