Adding aprepitant to chemotherapy was linked to longer survival in patients with non-luminal breast cancers, especially triple-negative breast cancer.

Experienced oncology nurses and APPs can help nurses newer to the field understand who is more at risk of opioid addiction, says expert Ronald Bleday, MD.

Panelists discuss how proactive monitoring for ALK inhibitor adverse effects through regular lipid panels, liver function tests, and patient education about red flag symptoms such as bradycardia or cognitive changes enables early intervention and successful dose management.

Panelists discuss how the unprecedented 5-year progression-free survival benefit (60% vs 8%) demonstrated in the CROWN trial supports starting with the most effective treatment (lorlatinib) up front rather than sequential therapy approaches.

Adding sonrotoclax to zanubrutinib led to deep and durable response in relapsed or refractory mantle cell lymphoma, according to EHA Congress data.

Explore essential mental health support strategies for older adults with cancer, addressing grief, community resources, and tailored care approaches.

Panelists discuss that talquetamab dose modifications are guided primarily by patient symptoms and adverse effects, with treatment pauses for significant toxicities or infections, while response monitoring relies on regular myeloma labs, imaging, and physical exams to ensure safety and efficacy.

Panelists discuss how talquetamab’s unique GPRC5D-related toxicities are managed proactively using International Myeloma Working Group guidelines, balancing outpatient delivery with vigilant monitoring and tailored cytokine release syndrome prophylaxis strategies.

Oncology nurses can ensure patients with non–small cell lung cancer receive the optimal treatment quickly by understanding comprehensive genomic profiling.

2025 ICE-T Conference presenters explain what nurses and APPs should take into account as immune cell effector therapies become more widely used.

Hope S. Rugo, MD, FASCO, emphasized the importance of educating patients about proactive rash and diarrhea management while taking PI3K/AKT inhibitors.

Pooled data from early-phase trials suggest JSKN003 is tolerable and active in patients with heavily pretreated HER2-positive disease.

Panelists discuss City of Hope’s multidisciplinary approach, highlighting pharmacists providing medication guidance, social workers offering emotional support, and palliative care specialists managing symptoms, while consultants such as cardiologists and infectious disease experts address specific health issues to ensure coordinated, personalized care; complementary therapies such as acupuncture and mindfulness help manage adverse effects like neuropathy, and support groups foster community and resilience among patients and caregivers throughout their myeloma journey.

Panelists share that despite initial emotional challenges, multiple myeloma treatment with targeted combination therapies was generally well tolerated, with manageable adverse effects—especially after adjusting dexamethasone—and strong health care team support, enabling patients to maintain quality of life and continue regular activities throughout therapy.

A generic version of ibrutinib was granted tentative approval by the FDA for use in CLL and SLL with 17p deletion and Waldenström macroglobulinemia.

Establishing a routine early in treatment helps proactively manage adverse effects associated with CDK4/6 inhibitors, says Kimberly Podsada, BSN, RN, MSN, NP-C, CNS.

Panelists discuss the critical role of patient education and multidisciplinary coordination in managing immunotherapy side effects, emphasizing proactive symptom monitoring, timely communication, tailored support, and collaborative care led by the oncologist to ensure safe and effective toxicity management.

Panelists discuss the importance of vigilant, patient-centered monitoring for metastatic melanoma patients with high disease burden on immunotherapy, emphasizing clear communication about variable treatment responses, proactive symptom tracking, differentiation of true progression from pseudoprogression, and integration of clinical assessments with biomarkers like lactate dehydrogenase and circulating tumor DNA to guide optimal care.

Paolo Tarantino, MD, PhD, explains that the chemotherapy-related toxicities from an ADC are more likely to limit dosage for patients with cancer.

The addition of retifanlimab to chemotherapy increased progression-free survival in patients with advanced squamous cell carcinoma of the anal canal.

Panelists discuss how treatment selection between lorlatinib and alectinib for ALK-positive non–small cell lung cancer (NSCLC) should consider both efficacy data favoring lorlatinib and patient-specific factors such as neuropsychiatric history or cardiovascular comorbidities that might favor alectinib.

Panelists discuss how a 48-year-old fitness instructor with ALK-rearranged stage IV lung cancer and bone metastases was successfully treated with alectinib, experiencing manageable adverse effects while returning to modified teaching activities.

While CIML natural killer immunotherapy can result in infection-like reactions, required prior chemo may cause infections, shared Wenxin (Vincent) Xu, MD.

The investigational BET inhibitor is being investigated combined with abemaciclib or cisplatin/etoposide in NUT carcinoma in 2 clinical trials.

Panelists discuss updated safety findings from GPRC5D-targeted bispecific therapy in relapsed/refractory multiple myeloma, highlighting manageable toxicity—including low infection rates and infrequent neurologic effects like ataxia—alongside sustained efficacy and durability, reinforcing its value as a well-tolerated option for patients ineligible for or resistant to BCMA-directed treatments.