Raghav Sundar on New Ways to Potentially Reduce CIPN

Raghav Sundar, MBBS, MRCP, MMed, National University Health System, Singapore, discusses the development of a new device that may be able to reduce chemotherapy-induced peripheral neuropathy (CIPN).

Raghav Sundar, MBBS, MRCP, MMed, National University Health System, Singapore, discusses the development of a new device that may be able to reduce chemotherapy-induced peripheral neuropathy (CIPN).

The device that was developed covers and cools patients’ arms and legs during chemotherapy infusion. By decreasing the temperature and thereby the blood flow, a smaller amount of chemotherapy will end up in the extremities, preventing CIPN.

A clinical trial was conducted that involved patients with breast cancer who were receiving weekly placlitaxel (Abraxane) infusions. Patients were monitored with temperature sensors and nerve-conducting studies. The proof-of-concept study showed that this may be a promising method to reduce CIPN.