Raghav Sundar on New Ways to Potentially Reduce CIPN

June 16, 2016
Raghav Sundar, MBBS, MRCP, MMed

Raghav Sundar, MBBS, MRCP, MMed, National University Health System, Singapore, discusses the development of a new device that may be able to reduce chemotherapy-induced peripheral neuropathy (CIPN).

Raghav Sundar, MBBS, MRCP, MMed, National University Health System, Singapore, discusses the development of a new device that may be able to reduce chemotherapy-induced peripheral neuropathy (CIPN).

The device that was developed covers and cools patients’ arms and legs during chemotherapy infusion. By decreasing the temperature and thereby the blood flow, a smaller amount of chemotherapy will end up in the extremities, preventing CIPN.

A clinical trial was conducted that involved patients with breast cancer who were receiving weekly placlitaxel (Abraxane) infusions. Patients were monitored with temperature sensors and nerve-conducting studies. The proof-of-concept study showed that this may be a promising method to reduce CIPN.