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Opinion|Videos|May 22, 2025

Innovative Symptom Monitoring in CML: Leveraging Technology and Patient-Reported Outcomes

Panelists discuss how innovative approaches to symptom monitoring incorporate multifaceted technology and team-based strategies, including electronic patient-reported outcome tools integrated with electronic medical record (EMR) systems, dedicated nurse coordinators for regular check-ins, specialized pharmacy services for medication education, and a comprehensive team approach involving various health care professionals to maintain consistent communication, ensure proper follow-up, and address potential barriers to adherence ranging from adverse effects to social and financial issues.

Episodes in this series

2 experts are featured in this series.

EP. 1 How Has the CML Treatment Landscape Evolved Over the Past 5 Years?

2 experts are featured in this series.

EP. 2 Understanding the Significance of Nilotinib's New Formulation

2 experts are featured in this series.

EP. 3 Addressing the Unmet Need in CML Treatment for Patient Treatment Adherence

2 experts are featured in this series.

EP. 4 The Impact of Cardiotoxicity Risks in CML: Navigating Dietary Guidelines with TKIs

2 experts are featured in this series.

EP. 5 Reducing Treatment Burdens: The Role of APPs in Enhancing CML Patient Quality of Life

2 experts are featured in this series.

EP. 6 Monitoring CML Patients: Effective Symptom Management Strategies for APPs

2 experts are featured in this series.

EP. 7 Empowering CML Patients: Why Open Communication About Symptoms Matters

2 experts are featured in this series.

EP. 8 Enhancing Adherence Through Patient Education: How Providers Can Support CML Patients on TKIs

2 experts are featured in this series.

EP. 9 The Impact of Medication Adherence on CML Outcomes

2 experts are featured in this series.

EP. 10 Promoting High Adherence in CML Patients: Proven Strategies for Health Care Providers

2 experts are featured in this series.

EP. 11 Rethinking CML Treatment: How New Treatments Are Improving Patient Medication Compliance and Adherence

2 experts are featured in this series.

EP. 12 Managing TKI Adverse Effects: Best Practices for Nilotinib and Other TKIs

2 experts are featured in this series.

EP. 13 Comparing TKI Adverse Effect Profiles

2 experts are featured in this series.

EP. 14 Innovative Symptom Monitoring in CML: Leveraging Technology and Patient-Reported Outcomes

2 experts are featured in this series.

EP. 15 Balancing Disease Control and Adverse Effect Management: Expert Insights in CML Treatment

Innovative Approaches to CML Symptom Monitoring: Clinical Summary

Technology-Enhanced Monitoring Solutions

Digital Patient-Reported Outcomes

EMR-integrated surveys: Electronic questionnaires delivered through patient portals or mobile applications
Regular assessment schedule: Weekly symptom questionnaires to capture evolving issues
Alert-based system: Automated notifications to clinical team when concerning changes are reported
Structured symptom tracking: Standardized questionnaires enabling systematic monitoring over time

Multidisciplinary Monitoring Approach

Coordinated Care Team Roles

Dedicated nurse coordinators: Scheduled proactive check-ins following tyrosine kinase inhibitor (TKI) initiation or modification
Specialized pharmacy services: Pharmacists dedicated to oral oncology providing:
- Medication education
- Adverse effect counseling
- Additional monitoring touchpoint
- Trust-building interaction outside traditional clinical encounters
Provider monitoring: Regular clinical assessment of both disease response and quality of life
Mental health professionals: Support for psychological aspects of chronic disease management
Social workers: Assistance with financial barriers and social determinants affecting adherence

Proactive Patient Engagement

Intentional touchpoints: Scheduled interactions beyond standard appointments
Telephone follow-ups: Brief calls to assess TKI tolerance and adverse effects
Appointment optimization: Flexibility to accelerate visits when issues arise
Continuous communication: Multiple channels for patients to report concerns

Implementation Considerations

Comprehensive Monitoring Focus

Regular PCR monitoring and quality-of-life assessment
Prevention of patient disengagement due to just taking a pill perception
Systematic approach to following patients who miss appointments

The implementation of these innovative monitoring approaches creates multiple opportunities for intervention, enhances adherence through supportive care, and reinforces the team-based nature of successful long-term chronic myeloid leukemia (CM)L management.

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