Osimertinib/Chemo Boosts Survival in Frontline EGFR+ NSCLC
FLAURA2 data show osimertinib plus chemotherapy significantly improves overall survival vs osimertinib alone in frontline EGFR+ advanced NSCLC.
Lutetium Lu 177 Dotatate Brings Partial Response in Metastatic BP-NETs
Lutetium Li 177 dotatate was linked with partial responses in patients with metastatic bronchopulmonary neuroendocrine tumors, per real-world data.
Rx Road Map: Durvalumab for Endometrial Cancer
Read an advanced practice nurse's tips for treating patients with endometrial cancer with durvalumab.
FDA Accepts Relacorilant NDA for Platinum-Resistant Ovarian Cancer
Relicorilant’s new drug application for platinum-resistant ovarian cancer has been accepted by the FDA.
Tepotinib Shows Manageable Safety in MET Exon 14+ NSCLC
Tepotinib was associated with frequent but manageable adverse events in MET exon 14–positive NSCLC, with peripheral edema most common.
Gemcitabine Intravesical System Receives FDA OK for NMIBC
Formerly known as TAR-200, gemcitabine intravesical system has received the FDA’s approval for use in patients with BCG-unresponsive NMIBC.
Ivonescimab/Chemo Ups PFS After Third-Generation TKI in EGFR+ NSCLC
Adding ivonescimab to chemotherapy improved PFS for patients with EGFR-mutated non–small cell lung cancer after treatment with a third-generation TKI.
Subcutaneous Daratumumab Reduces Smoldering Myeloma Progression
New AQUILA data show PFS improvement in patients with smoldering multiple myeloma who were treated with subcutaneous daratumumab vs active monitoring.
Where Is the Care in Health Care?
GLP-1a Associated With Better Outcomes for Those With Polycythemia Vera
Mortality, progression, and venous thromboembolism were among outcomes improved for patients with polycythemia vera taking a GLP-1a.
Structure to Safety: A Nurse's Guide to Safe ADC Care
Familiarity with each component of antibody-drug conjugates helps nurses and APPs deliver proactive adverse event management to patients with cancer.
Venetoclax Combo Did Not Increase OS in Intermediate/High-Risk MDS
Patients with intermediate- or high-risk MDS experienced a higher modified overall response rate with the venetoclax/azacitidine vs placebo/azacitidine.
Understanding the Unique Roles of Oncology Teams in Biology-Guided RT
Biology-guided radiotherapy involves teamwork across multiple specialists, according to Samantha Bianzon, BSN, RN.
Opinion: Nursing Considerations for Emerging CLDN6-Targeted Therapies
Understanding which patients may benefit from CLDN6-targeting immunotherapy and recognizing potential adverse effects is essential for oncology nurses.
How to Manage ICANS in Patients With Hematologic Cancers
Nurses must stay up to date on novel agents and their toxicities to properly monitor for and manage immune effector cell-associated neurotoxicity syndrome.
Patient Views on Skin-Related AEs May Affect Cancer Treatment Choices
Survey results show patients may overestimate dermatologic AEs from anti-cancer therapies, raising concerns for treatment adherence.
Nurses Are Key to Reducing Opioid Use After Colorectal Surgery
Ronald Bleday, MD, discusses how nurses support a step-wise model to minimize opioid use after colorectal surgery while ensuring safe pain control.
A Nurse’s Overview of First-Line Treatment for HR+ Metastatic Breast Cancer
Experts share advice on tailoring frontline treatment and managing toxicities for individuals with hormone receptor–positive metastatic breast cancer.
CDK4/6 Inhibitors: How to Tailor Treatment Choices by AEs
Nurse practitioners give their advice on making treatment choices based on the patient’s medical history and preferences.
Rina-S Given Breakthrough Therapy Designation in Endometrial Cancer
The investigational ADC rinatabart sesutecan was given breakthrough therapy designation for use in patients with recurrent/progressive endometrial cancer.
Research Provides Learning Opportunities for Oncology Nurses
Oncology nurses are needed in research roles, which can provide experience with new therapies, explained Josh Settlemire, MSN, RN, OCN.
Managing CRS in Hematologic Cancers: A Nursing Perspective
CRS is a common but manageable toxicity of CAR T-cell therapy and bispecific antibodies. Learn strategies to identify and manage this adverse effect.
Safer Care in Breast Cancer: Expert Advice for Managing ADC Toxicities
Paolo Tarantino, MD, PhD, discusses ADC structure, toxicity, and nursing consideration for the treatment of patients with breast cancer.
IMvigor011 Confirms ctDNA-Guided Care in Bladder Cancer
IMvigor011 showed significant improvement in survival outcomes with adjuvant atezolizumab in ctDNA-positive MIBC.
Opioid Reduction in Surgical Oncology Supported by Cultural Shift
A significant reduction of opioid use in patients after colorectal surgery was supported by clinician and patient compliance, says Ronald Bleday, MD.
Transformative Care: A Nurse Guide to Novel Therapies in Blood Cancers
Beyond administering CAR T-cell therapy and bispecifics, oncology nurses must apply proactive, supportive care and an understanding of complex treatments.
How Can Nurses Provide Better Symptom Management for Patients With MPNs?
A nurse-led clinic to aid in patient-reported symptom burden had high patient satisfaction.
Personalizing Neurotoxicity Monitoring After CAR T-Cell Therapy
Neurotoxicities can be monitored long term with personalized questions, according to Mary Steinbach, DNP, APRN.
Amphiphile Vaccine Extends RFS in KRAS+ Pancreatic Cancer
In a phase 1 study, ELI-002 2P improved relapse-free survival in pancreatic and colorectal cancer, with stronger benefit in patients with T-cell responses.
Personalizing CDK4/6 Inhibitor Care to Reduce Adverse Events
Oncology nurses play a key role in monitoring, managing, and personalizing CDK4/6 inhibitor treatment to minimize toxicities and protect quality of life, according to Courtney Moore, APRN, FNP-C, OCN.
Nurses Lead Toxicity Monitoring in Indolent Lymphoma Care
Safety Management With Amivantamab Plus Lazertinib in NSCLC