MR-Linac Reduced Radiation to Healthy Brain Tissue in Glioma
Weekly MR-Linac adaptive radiotherapy limited exposure to normal brain tissue in patients with high-grade glioma.
Talazoparib Plus Enzalutamide Improves Survival in Metastatic CRPC
Adding talazoparib to enzalutamide improved survival in patients with metastatic castration-resistant prostate cancer.
NT-I7 Enhances CAR T-Cell Efficacy in DLBCL
NT-17, a long-acting IL-7 agent, enhances CAR T-cell factors associated with efficacy in patients with relapsed/refractory DLBCL when administered 21 days post-CAR T infusion.
FDA Approves Inavolisib Regimen for PIK3CA-mutated, HR+, HER2— Breast Cancer
Inavolisib plus palbociclib and fulvestrant was approved for the treatment of PIK3CA-mutant, HR-positive, HER2-negative locally advanced or metastatic breast cancer.
SCLC Staging Determines Treatment, Adverse Events
The staging of small cell lung cancer significantly impacts treatment plans and potential side effects.
AbbVie Submits BLA to Telisotuzumab Vedotin for NSCLC
A supplemental biologics license application was submitted for telisotuzumab vedotin for the treatment of metastatic EGFR wild-type nonsquamous non–small cell lung cancer.
Surgical Technique May Preserve Fertility, Boost QoL With Pelvic Radiation
Pelvic transposition may improve quality of life and preserve fertility in patients with gynecologic cancer undergoing pelvic radiation.
Finding the ‘Right Fit’ for ER+ Breast Cancer After Aromatase Inhibitor AEs
A nurse practitioner discussed considerations for managing aromatase inhibitor-related joint pain in patients with breast cancer.
WHO Updates Cervical Cancer Prevention Guidelines
The World Health Organization updated their guidelines to include CINtec PLUS Cytology for gynecologic cancer prevention.
Oncology Nurses, APPs Play a ‘Unique Role’ in Sarcoma Treatment
An expert explained the role oncology nurses and advanced practice providers play in caring for patients with sarcoma during treatment.
Adding Nivolumab to Standard Radiotherapy Better Biochemical Recurrence Outcomes in Prostate Cancer
The addition of nivolumab to radiotherapy significantly improved freedom from biochemical recurrence in patients with high-grade prostate cancer.
Allogeneic CAR T-Cell Therapy Is Safe, Effective in Heavily Pretreated Myeloma
P-BCMA-ALLO1 elicited high response rates and a manageable safety profile in heavily pretreated, relapsed/refractory multiple myeloma.
Oral Drugs Put a Focus on Adherence, Communication in Second-Line Breast Cancer
Oral drugs in the HR-positive, HER2-negative metastatic breast cancer space put a focus on clear patient-provider communication about adherence and adverse events.
Acalabrutinib Gets Priority Review for Frontline MCL Treatment
The FDA granted a priority review to acalabrutinib for the treatment of previously untreated adults with mantle cell lymphoma.
FDA Approves Perioperative Nivolumab Regimen for NSCLC
The FDA approved neoadjuvant nivolumab plus chemo, followed by adjuvant nivolumab for non-small cell lung cancer without EGFR mutations or ALK rearrangements.
Cilta-Cel Continues to Boosts Survival in Pretreated Myeloma
Follow-up from the CARTITUDE-4 trial showed that cilta-cel improved survival over standard of care in pretreated myeloma.
Cilta-Cel Is Safe, Efficacious in Real-World Treatment of Myeloma
Cilta-cel led to high response rates and a promising safety profile in a real-world population of patients with relapsed/refractory myeloma.
Belantamab Mafodotin, KRd Is Promising in Relapsed/Refractory Myeloma
Belantamab mafodotin plus KRd had a a manageable safety profile and deep responses in pretreated multiple myeloma.
Anthracyclines Boost Survival, Increases Hospital Time in AML
Older adults with acute myeloid leukemia treated with anthracyclines tended to live longer, but also had more time spent in the hospital compared with those treated with HMAs.
FDA Committee Votes Against PD-L1 as a Predictive Biomarker for Gastric Cancers
ODAC voted against the use of PD-L1 expression as a predictive biomarker in gastric cancers.
Oncology Nurses Are the ‘Frontlines to Nutritional Deficiencies’
When it comes to cancer-related malnutrition, nurses should look out for more signs than just weight loss.
Supporting Caregivers While Patients Receive Cancer Care
Oncology nurses and APPs play a role in supporting caregivers while the patient they care for receives a diagnosis and cancer treatment.
FDA Approves Selpercatinib for RET+ Medullary Thyroid Cancer
The agency approved selpercatinib for the treatment of patients with advanced or metastatic, RET-mutant medullary thyroid cancer.
Belantamab Plus VRd Is Safe, Efficacious in Transplant-Eligible Myeloma
Belantamab plus VRd led to promising outcomes in newly diagnosed transplant-eligible myeloma, study results showed.
Understanding the Role of an Oncology Research Nurse
An oncology research nurse balances patient care with rigorous data collection, emphasizing communication and collaboration to advance cancer research.
RX Road Map: Glofitamab-gxbm (Columvi)
FDA Approves Post-Chemoradiation Osimertinib for Advanced NSCLC
The FDA approved osimertinib for locally advanced, unresectable stage III EGFR-mutated non-small cell lung cancer.
Neoadjuvant ICIs May Improve Efficacy Outcomes in Early-Stage TNBC
Neoadjuvant immune checkpoint inhibitors plus chemotherapy also improved efficacy outcomes in PD-L1-positive/ERBB2-negative tumors.
Non-Operative Management of Rectal Cancer Does Not Worsen Distant RFS
Distant relapse-free survival was maintained with non-operative management of pMMR locally advanced rectal cancer.
Chlorhexidine Dressings Decrease Risk for Infection in Patients With Cancer
Chlorhexidine dressings, along with proper patient education, are key in preventing central line-associated blood stream infections in patients with cancer.
Nurses Lead Toxicity Monitoring in Indolent Lymphoma Care
Osimertinib/Chemo Boosts Survival in Frontline EGFR+ NSCLC
Lutetium Lu 177 Dotatate Brings Partial Response in Metastatic BP-NETs
Safety Management With Amivantamab Plus Lazertinib in NSCLC