Expert Discusses Recent CLL Approval
The recent approval of ibrutinib plus obinutuzumab is a major advancement in the chronic lymphocytic leukemia space.
Suman Kambhampati, MD, the co-director of blood cancer research at Sarah Cannon Cancer Institute at HCA Midwest Health, discusses the recent FDA approval of ibrutinib (Imbruvica) plus obinutuzumab (Gazyva) for the frontline treatment of patients with chronic lymphocytic leukemia (CLL).
The approval was based on the phase III iLLUMINATE trial, which showed that ibrutinib plus obinutuzumab was the first non-chemotherapy combination that was extremely effective in treating nearly all subtypes of patients with CLL. The combination elicited a longer progression-free survival (PFS), nearly a 100% response rate, and better complete responses (CR) than treatment with ibrutinib alone, making it an extremely exciting treatment option for these patients.
Shared Model of Care Post-HCT Offers Safe Follow-Up, Reduces Patient Burden
Published: March 19th 2025 | Updated: March 19th 2025Alternating post-HCT care between specialized facilities and local cancer centers produced noninferior non-relapse mortality and similar quality of life to usual care.
