Angelica Welch

Articles

Optimal Strategies Expand How Oncologists Target Treatment in NSCLC

November 29, 2018

The acceptance of next-generation sequencing (NGS) platforms and cell-free DNA (cfDNA) have enabled oncologists to more specifically target genetic mutations in the treatment of patients with non–small cell lung cancer (NSCLC), according to Benjamin P. Levy, MD.

FDA Grants Olaparib Priority Review for Frontline Maintenance in Ovarian Cancer

November 12, 2018

The FDA has granted a priority review designation to a supplemental new drug application (sNDA) for olaparib (Lynparza) tablets for use as a maintenance therapy in patients with newly-diagnosed, BRCA-positive advanced ovarian cancer who achieved a complete or partial response to standard frontline platinum-based chemotherapy.

Olaparib Significantly Improves PFS in Advanced BRCA+ Ovarian Cancer

November 06, 2018

The PARP inhibitor olaparib (Lynparza) significantly improved progression-free survival (PFS) as frontline maintenance therapy in women with BRCA-positive advanced ovarian cancer, according to findings reported at the 2018 European Society of Medical Oncology Congress.

Asymptomatic, Young Patients With MCL May Avoid Active Treatment

September 25, 2018

Frontline therapy may be able to be avoided in asymptomatic, young, fit patients with mantle cell lymphoma (MCL), explained Simon Rule, MD, PhD, in a presentation during the 2018 SOHO Annual Meeting. Active treatment in this patient population could potentially lead to unnecessary toxicities, he added.

Carfilzomib-Based Regimens Deemed Safe in Multiple Myeloma

September 21, 2018

Two trials have shown that carfilzomib (Kyprolis)-based regimens appeared to be a safe and effective treatments for all patients with multiple myeloma, according to updated data from the ASPIRE and ENDEAVOR trials presented at the 2018 SOHO Annual Meeting.

Advances in HER2+ Breast Cancer

March 08, 2018

A wave of novel treatments and FDA approvals has recently swept through the HER2-positive breast cancer space. Kimberly L. Blackwell, MD, oncologist at Duke Cancer Institute, discusses these recent advancements.