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Findings from the PACIFIC-R trial showed that patients with EGFR-mutated non-small cell lung cancer experienced shorter progression-free survival with durvalumab than patients with EGFR-wildtype disease. 

Durvalumab Garners Similar OS, Albeit Varied PFS, Outcomes in EGFR+ and EGFR-Wildtype NSCLC Subgroups 

Quizartinib plus standard intensive induction and consolidation therapy was associated with longer survival rates in patients with FLT3-ITD–positive acute myeloid leukemia. 

Quizartinib Extends Overall Survival Across Multiple Subgroups in FLT3-ITD+ AML 

The confirmed objective response rate with repotrectinib was 79% among tyrosine kinase inhibitor (TKI)-naïve patients and 38% among TKI-pretreated patients. 

Repotrectinib Showcases Early Intracranial Responses in Select ROS1+ NSCLC 

The median progression-free survival was 25.5 months with osimertinib plus chemotherapy and 16.7 months with osimertinib alone. 

Osimertinib May Be More Effective in Frontline EGFR+ NSCLC When Combined With Chemo

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Lindsay Fischer is an editor at ONN. She joined MJH life sciences in 2021 after graduating from Rutgers University with majors in both English and Spanish and a minor in creative writing. When she is not writing, or researching the latest oncology nursing news, Lindsay is an amateur backpacker and rollerblader. Email Lindsay at lfischer@mjhlifesciences.com

Articles

Ellen Miller, MSN, FNP-BC, an oncology nurse practitioner, explains how she uses wreath-making to maintain a healthy work-life balance. 

Oncology Nurses Need a ‘Creative Outlet’

Immuno-oncology regimens were linked with improved long-term survival among patients with hepatocellular carcinoma.

Immunotherapy-Based Regimens Are Associated With OS Advantage in HCC

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A majority of adult patients with β-thalassemia who require regular red blood cell (RBC) transfusions experienced clinically meaningful and durable transfusion burden reduction associated with luspatercept (Reblozyl) in the phase III BELIEVE trial. 

Reducing Transfusion Burden in Patients With Beta-Thalassemia

Lynne Lederman, PhD

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