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Findings from the PACIFIC-R trial showed that patients with EGFR-mutated non-small cell lung cancer experienced shorter progression-free survival with durvalumab than patients with EGFR-wildtype disease. 

Durvalumab Garners Similar OS, Albeit Varied PFS, Outcomes in EGFR+ and EGFR-Wildtype NSCLC Subgroups 

Quizartinib plus standard intensive induction and consolidation therapy was associated with longer survival rates in patients with FLT3-ITD–positive acute myeloid leukemia. 

Quizartinib Extends Overall Survival Across Multiple Subgroups in FLT3-ITD+ AML 

The confirmed objective response rate with repotrectinib was 79% among tyrosine kinase inhibitor (TKI)-naïve patients and 38% among TKI-pretreated patients. 

Repotrectinib Showcases Early Intracranial Responses in Select ROS1+ NSCLC 

The median progression-free survival was 25.5 months with osimertinib plus chemotherapy and 16.7 months with osimertinib alone. 

Osimertinib May Be More Effective in Frontline EGFR+ NSCLC When Combined With Chemo

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The pathological complete response among patients who received durvalumab plus chemotherapy was 17.2% vs 4.3% in the placebo plus chemotherapy arm. 

Perioperative Durvalumab Plus Chemo Boosts pCR, EFS in Resectable NSCLC

Data suggest that frontline treatment brentuximab vedotin elicits superior outcomes in patients with Hodgkin Lymphoma, regardless of PET2 results. 

Interim PET2 Scans May Be Redundant in Frontline Brentuximab Vedotin Regimens Treatments for Hodgkin Lymphoma

The FDA has granted belzutifan priority review designation based on data from the phase 3 LITESPARK-005 trial. 

FDA Launches Priority Review of Belzutifan for Previously Treated Advanced RCC

Lindsay Fischer is an editor at ONN. She joined MJH life sciences in 2021 after graduating from Rutgers University with majors in both English and Spanish and a minor in creative writing. When she is not writing, or researching the latest oncology nursing news, Lindsay is an amateur backpacker and rollerblader. Email Lindsay at lfischer@mjhlifesciences.com

Cheryl VerStrate, DNP, AGPCNP-BC, OCN, explains the pitfalls with at-home genomic tests and why nurses must be ready to talk to their patients about genetic counseling. 

Are At-Home Genomic Tests Such as 23andMe Ethical?

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As oncology nurses, we have too often seen young adults who, successfully cured of their childhood cancers, return with serious or debilitating health concerns or even a secondary malignancy as a late effect from chemotherapy or radiation.

Late-Effects Clinic, Passport for Care Support Survivors of Childhood Cancers

Kathryn Wells, RN, MS, CPNP, CPON

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