Laura Tang, MD, PhD, a pathologist at Memorial Sloan Kettering Cancer Center, discusses the classifications of advanced neuroendocrine tumors (NETs). 

NETs are classified as well-differentiated or poorly-differentiated. 

Patients with well-differentiated, high grade (G3) NETs generally do not experience symptoms and their tumors are often diagnosed incidentally. 

Patients with poorly-differentiated tumors are typically very ill and present with dramatic symptoms such as abdominal pain, weight loss, and jaundice. 

Laura Tang, MD, PhD

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Laura Tang on Classifications of Neuroendocrine Tumors