Breast Cancer

Mail-in DNA tests may not provide enough information to people looking for answers about their genetic predisposition to cancer.

Nadine M. Tung, MD, discussed the role of PARP inhibitors for patients with BRCA-positive breast cancer and the importance of genetic testing.

Direct-to-consumer genetic testing enables individuals to pursue testing independently and without interference from a healthcare professional. But is there a downside?

BLU-667 appeared to be well-tolerated and had broad clinical benefit among patients with advanced, RET-altered solid tumors who progressed on prior therapies, according to study findings from a phase I clinical trial presented at the AACR Annual Meeting 2018.

The National Comprehensive Cancer Network (NCCN) guidelines on breast cancer now allow physicians to pinpoint the women who are most likely to benefit from post-mastectomy radiation using the latest targeted testing techniques.

Systematic exposure to bright morning light could help patients with cancer and survivors sleep better and experience less fatigue.

A filgrastim (Neupogen) biosimilar, EP2006, recently produced safety results equivalent to those observed with referent filgrastim in a combined analysis of 2 phase III breast cancer studies from the United States and Europe.

CE lesson worth 1 contact hour that is intended to advanced practice nurses, registered nurses, and other healthcare professionals who care for patients with cancer.

Nurses should be aware of the phenomenon of breast implant-associated anaplastic large cell lymphoma.

A group of researchers in the northeast United States conducted a study to explore how women become informed about breast cancer surgery options.

Endocrine therapy can reduce tumor size in patients with ER-positive breast cancer. It can even help some patients avoid chemotherapy or even surgery. Deciding how long to continue this therapy can be tricky though.

By taking the nonthreatening approach of consulting a genetic counselor, plus the simple act of sending out a freshly collected 1-cc sample of saliva, I will affect not only my health but also the well-being of my daughters, son, and grandchildren.

The latest revision of the staging manual for breast cancer from the American Joint Committee on Cancer (AJCC) codifies advanced knowledge of the role of biologic factors in cancer.

The availability of PARP inhibitors for the treatment of patients with BRCA-mutant metastatic breast cancer has the potential to usher in a new era for targeted therapies.

Breast cancer survivors who exercise could reduce their risk of cardiovascular events, stroke, and diabetes, study shows.

Ribociclib (Kisqali) improves progression-free survival (PFS) in pre- or perimenopausal women with hormone receptor–positive, HER2-negative advanced or metastatic breast cancer. These results, shared at 2018 Miami Breast Cancer Conference, were sustained across patient subgroups.

Palbociclib (Ibrance), a CDK 4/6 inhibitor, demonstrated significant efficacy in combination with the aromatase inhibitor letrozole (Femara) in the frontline setting of estrogen receptor (ER)-positive, HER2-negative, postmenopausal metastatic breast cancer in phase III PALOMA-2 study.

A wave of novel treatments and FDA approvals has recently swept through the HER2-positive breast cancer space. Kimberly L. Blackwell, MD, oncologist at Duke Cancer Institute, discusses these recent advancements.

Radiotherapy treatments for Hodgkin lymphoma may raise the risk of certain breast cancer subtypes, a study of data on women survivors from the Surveillance, Epidemiology, and End Results (SEER) registries revealed.

One out of three men with breast cancer does not receive adequate treatment, according to results of a global study which were published in Annals of Oncology.

Predicting survival outcomes for patients with metastatic triple-negative breast cancer (mTNBC) is now possible using liquid biopsy, according to results from a retrospective study published in the Journal of Clinical Oncology.

Based on data from the phase III MONARCH 3 trial, the FDA has approved abemaciclib (Verzenio) for use in combination with an aromatase inhibitor for the frontline treatment of postmenopausal women with hormone receptor (HR)-positive, HER2-negative advanced or metastatic breast cancer.

Many adolescent and young adult (AYA) survivors of cancer end up "lost to follow-up," according to recent research. Nurses charged with patient education should take heed, and be sure to stress the importance of follow-up care to their AYA patients and their families.

Patient navigation is playing an increasingly vital role in guiding patients with breast cancer through the maze of the American healthcare system. The Patient Navigation Initiative is a pioneering project of Susan G. Komen of Greater New York City focused on helping women overcome barriers to care, which leads to improved outcomes.

Incorporating patient navigation into cancer care makes good business sense. This is the second in a series of articles about of patient navigation.

Empathy and cultural sensitivity enable navigators to be effective champions for patients with cancer. This is the third in a series of articles about patient navigation.

In just over 5 years, the growth and development in the field of breast cancer have been astronomical. Julie Nangia, MD, Assistant Professor of Medicine, Baylor College of Medicine, discusses the recent explosion of knowledge about non-BRCA genes, and the significant progress in therapies targeted to BRCA mutation carriers.

Cryotherapy delivered through frozen gloves and socks during paclitaxel (Taxol) infusion dramatically reduced objective and subjective symptoms of chemotherapy-induced peripheral neuropathy (CIPN) in a small study of patients with breast cancer.

Patients whose cancers have metastasized to the brain or central nervous system are often excluded from clinical trials, but now, new guidelines may help researchers identify appropriate clinical trials in which these people may be included.

Changes in cognitive function, or chemobrain, are common among patients who survive breast cancer. However, limited efforts have been put in to understanding or managing these cognitive changes in survivors. Now, there is a web site that can help with just that.