Tisagenlecleucel (Kymriah), Novartis' newly approved CAR T-cell therapy, will be put on the market with a price of $475,000 for a single infusion, an amount that is within the range anticipated by oncologists and that Novartis characterized as well below a price level that could be justified on cost.
The FDA issued a historic approval of the first Chimeric Antigen Receptor (CAR) T-Cell Therapy, authorizing the use of tisagenlecleucel (Kymriah) for the treatment of patients up to 25 years of age with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory or in second or later relapse.
Francisco J. Esteva, M.D., Ph.D. discussed genomic testing at the 16th Annual International Congress on the Future of Breast Cancer® (East).
The FDA has approved fulvestrant (Faslodex) for use in hormone receptor (HR)-positive, HER2-negative locally-advanced or metastatic breast cancer in postmenopausal women not previously treated with endocrine therapy.
A patient can experience less pain, a quicker healing time and potentially more normal kidney function, due to the minimally invasive aspect of robotic surgery, according to Ketan K. Badani, M.D.
A California woman has been awarded $417 million after alleging that Johnson & Johnson’s talcum-based Baby Powder led to ovarian cancer. The jury award may be the largest yet concerning the product.
In some ways, it’s the down side of optimism: A recent study has found that older people sometimes think they are capable of more activity than their caregivers say they are.
Clinicians are aware of established guidelines for post-treatment surveillance and follow-up of people who have been treated for cancer. But what do patients expect?
Lynparza tablets (olaparib) tablets were granted FDA approval as a maintenance therapy for patients with recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer, who are in a complete or partial response to platinum-based chemotherapy.
Artist Ryan Berardi’s work goes way beyond pretty pictures. In fact, his 3D animations of what can go wrong during chemotherapy paint a horrific scene.
Bladder cancer is uncommon, and is more often diagnosed at an advanced stage because it has symptoms that mimic other disorders.
Physical activity may be effective in mitigating cancer-related cognitive impairment. Prior studies show this may be a promising treatment. However, sample sizes were small and self-reported measures varied.
The novel combination of a neurokinin-1 (NK-1) receptor antagonist and the 5-HT3 receptor antagonist palonosetron (Aloxi), NEPA (Akynzeo) had non-inferior efficacy compared to a conventional aprepitant regimen for preventing chemotherapy-inducted nausea and vomiting (CINV).
The FDA has approved CPX-351 (Vyxeos), a fixed-combination of daunorubicin and cytarabine, for adult patients with either newly-diagnosed therapy-related acute myeloid leukemia (t-AML) ot AML with myelodysplasia-related changes (AML-MRC).
Ibrutinib has been approved for the treatment of adult patients with chronic graft versus hose disease (GVHD) following the failure of 1 or more lines of systemic therapy.
The FDA has approved enasidenib for patients with IDH2-Mutated acute myeloid leukemia (AML).
CD19 CAR T-cell therapy induced a high-response rate in patients with high-risk, ibrutinib-refractory chronic lymphocytic leukemia (CLL).
The FDA has granted accelerated approval to nivolumab (Opdivo) for the treatment of adult and pediatric patients with microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) metastatic colorectal cancer (mCRC).
A recent study has found that there may be no risk of increasing skin irritation by using antiperspirants for patients with breast cancer undergoing radiation.
A side-effect of some lung cancer treatments is turning some patient's gray hair darker again.
A 15-year brain tumor survivor offers advice and discusses the advances that have been made since his diagnosis.
Checkpoint inhibitors against PD-1 and PD-L1 have shown promise, both as monotherapies and in combination with chemotherapy for patients with triple-negative breast cancer (TNBC).
Oncology Nursing News spoke with an expert about coping strategies for those who have developed chemotherapy-induced peripheral neuropathy (CIPN).
For years, people believed that there was a link between vasectomies and prostate cancer.
A recent study found that women with breast cancer often have a network of people that they consult to help them make treatment decisions.
Rami Komrokji, MD, discusses the advances that have been made in myelodysplastic syndrome MDS in the past few years, as well as the MDS Clinical Research Consortium and its importance.
Ovarian cancer expert, David M. Gershenson, MD, from University of Texas MD Anderson Cancer Center discusses three treatments for some of the rare types of ovarian cancers and the challenges to treating these diseases.
Breast cancer expert Joyce O'Shaughnessy, MD, discusses the current treatments for metastatic triple negative breast cancer (TNBC) as well as potential options in the future.
