Team-Based Approach Essential in HCC CareMay 13th 2020
The implementation of a multidisciplinary team, which has demonstrated a marked survival advantage compared with single-provider care, is critical in hepatocellular carcinoma (HCC), particularly as it relates to the evolving role of radiation, surgical resection, liver transplantation, and systemic treatment, explained Neehar Parikh, MD.
Locoregional Treatments Still Key in HCC CareMay 11th 2020
A number of treatment options exist for patients with localized hepatocellular carcinoma (HCC), including surgical resection, transplantation, ablation, stereotactic body radiotherapy (SBRT), and embolization, said Riad Salem, MD, who added that a multidisciplinary team is needed to determine the optimal use of these approaches among newer novel systemic treatments.
HCC Treatment Continues to Improve, But Biomarkers Are Still NeededMarch 14th 2020
A flood of targeted therapy and immunotherapy options to both the first- and second-line settings of hepatocellular carcinoma (HCC) has had significant implications on the treatment of patients in this space and will likely create challenges regarding sequencing, said Richard S. Finn, MD.
Individualized Treatment Is Key for mCRCMarch 5th 2020
Key elements that should inform treatment decisions for patients with metastatic colorectal cancer (mCRC) include molecular profiling, tumor sidedness, and microsatellite instability–high (MSI-H)/mismatch repair deficient (dMMR) status, according to Michael J. Overman, MD.
Combination Therapy Bests Standard of Care in BRAF+ CRCJanuary 28th 2020
Encorafenib (Braftovi) plus cetuximab (Erbitux) with or without binimetinib (Mektovi) demonstrated longer maintenance of quality of life (QoL) on patient-reported assessments over current standard of care in the treatment of patients with BRAF V600E-mutant metastatic colorectal cancer.
Surufatinib Improves Outcomes in Advanced Pancreatic NETsJanuary 23rd 2020
Surufatinib improved progression-free survival (PFS) compared with placebo in patients with low- or intermediate-grade advanced pancreatic neuroendocrine tumors (pNETs) for whom there is no effective therapy, according to a preplanned interim analysis of the phase III SANET-p trial (NCT02589821) that was completed by an independent data monitoring committee (IDMC).
PARP Inhibitor Provides Another Option for Metastatic Pancreatic CancerJanuary 8th 2020
The metastatic pancreatic cancer paradigm has expanded to include frontline maintenance therapy with the PARP inhibitor olaparib (Lynparza), as it recently received the green light from the FDA with a December 2019 approval.
Quality of Life Data for PARP Inhibitor Shows Promise for Pancreatic Cancer TreatmentOctober 10th 2019
Results from the randomized phase 3 POLO trial are in, and the quality of life data shows promise for patients with metastatic pancreatic cancer who harbor a germline BRCA gene mutation.
Nurses Can Refer Patients to Reliable Stomach Cancer InformationSeptember 4th 2019
When one of your patients is diagnosed with gastrointestinal cancer, it can be difficult for them to cope with their diagnosis. However, as their Oncology nurse, you can help guide them to reliable patient resources on stomach cancer, like Debbie’s Dream Foundation.
Immunotherapy Combo Is Promising in MSI-H Colorectal CancerAugust 26th 2019
The frontline combination of nivolumab (Opdivo) and ipilimumab (Yervoy) showed a robust and durable clinical benefit in patients with metastatic colorectal cancer (mCRC) whose tumors are microsatellite instability–high (MSI-H)/mismatch repair deficient (dMMR)—a population with a historically poor prognosis, said Heinz-Josef Lenz, MD, FACP.
The Raymond Foundation Is Dedicated to Helping Patients and CaregiversJuly 4th 2019
At the 2019 Annual ASCO meeting in Chicago, Oncology Nursing News got the chance to speak with Martha Raymond, CEO and founder of the Raymond Foundation, and executive director at the GI Cancers Alliance.
FDA Approves Bevacizumab Biosimilar for 5 Cancer TypesJune 28th 2019
The Food and Drug Administration approved bevacizumab-bvzr (Zirabev) – a biosimilar for bevacizumab (Avastin) for the treatment of metastatic colorectal cancer; unresectable, locally advanced, recurrent or metastatic NSCLC; recurrent glioblastoma; metastatic renal cell carcinoma; and persistent, recurrent or metastatic cervical cancer.