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Opinion|Videos|March 5, 2025

Dose Modifications When Managing Side Effects with ALK Inhibitors

Key opinion leaders explore approaches to dose modifications or treatment pauses due to side effects, including examples where these adjustments significantly impacted patient outcomes.

Episodes in this series

EP. 1 Robert’s Journey With EGFR+ Metastatic NSCLC

EP. 1 Robert’s Journey With EGFR+ Metastatic NSCLC

EP. 2 Patient Guidance and Education of EGFR Inhibitor Therapies

EP. 2 Patient Guidance and Education of EGFR Inhibitor Therapies

EP. 3 Strategies to Managing Cardiotoxic AEs with Osimertinib

EP. 3 Strategies to Managing Cardiotoxic AEs with Osimertinib

EP. 4 Balancing Treatment Benefits and Toxicity: Managing Quality of Life in EGFR+ NSCLC Patients

EP. 4 Balancing Treatment Benefits and Toxicity: Managing Quality of Life in EGFR+ NSCLC Patients

EP. 5 Strategies of Dose Modifications of Osimertinib and Other EGFR Inhibitors

EP. 5 Strategies of Dose Modifications of Osimertinib and Other EGFR Inhibitors

EP. 6 Management of GI Toxicities in Osimertinib and other EGFR Inhibitors

EP. 6 Management of GI Toxicities in Osimertinib and other EGFR Inhibitors

EP. 7 Importance of Multidisciplinary Team in Managing AEs of EGFR Inhibitors

EP. 7 Importance of Multidisciplinary Team in Managing AEs of EGFR Inhibitors

EP. 8 Comparison of Safety Profiles of EGFR Inhibitors

EP. 8 Comparison of Safety Profiles of EGFR Inhibitors

EP. 9 Jason’s Journey with ALK+ Metatstatic NSCLC

EP. 9 Jason’s Journey with ALK+ Metatstatic NSCLC

EP. 10 Patient Education and Guidance on Lorlatinib and Other ALK Inhibitors

EP. 10 Patient Education and Guidance on Lorlatinib and Other ALK Inhibitors

EP. 11 Management of Neurotox AEs with Lorlatinib

EP. 11 Management of Neurotox AEs with Lorlatinib

EP. 12 Management of Hyperlipidemia and Weight Gain with Lorlatinib

EP. 12 Management of Hyperlipidemia and Weight Gain with Lorlatinib

EP. 13 Management of GI AEs with ALK Inhibitors

EP. 13 Management of GI AEs with ALK Inhibitors

EP. 14 Dose Modifications When Managing Side Effects with ALK Inhibitors

EP. 14 Dose Modifications When Managing Side Effects with ALK Inhibitors

EP. 15 Role of Multidisciplinary Strategies in care of ALK+ NSCLC Patients

EP. 15 Role of Multidisciplinary Strategies in care of ALK+ NSCLC Patients

EP. 16 Patient Factors in Treatment Selection of ALK Inhibitors

EP. 16 Patient Factors in Treatment Selection of ALK Inhibitors

Video content above is prompted by the following:

How do you approach dose modifications or pauses in treatment due to side effects?
Do you have any examples where these adjustments made a significant difference in patient outcomes?

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Joyce O’Shaughnessy, MD; Matthew P. Goetz, MD; Hope S. Rugo, MD, FASCO

Expert Guidance on Frequently Asked Questions Regarding the Use of ADCs in TNBC

Expert Guidance on Frequently Asked Questions Regarding the Use of ADCs in TNBC

Aditya Bardia, MD, MPH, FASCO; Erika P. Hamilton, MD; Virginia Kaklamani, MD, DSc

Evaluating the Latest Data and Ongoing Trials for Novel ADC Approaches in TNBC

Evaluating the Latest Data and Ongoing Trials for Novel ADC Approaches in TNBC

Aditya Bardia, MD, MPH, FASCO; Erika P. Hamilton, MD

Dissecting Clinical Trial and Real-World Data for ADCs in TNBC

Dissecting Clinical Trial and Real-World Data for ADCs in TNBC

Filipa Lynce, MD; Rita Nanda, MD

Breaking Down the Rationale for Targeting TROP2 in TNBC

Breaking Down the Rationale for Targeting TROP2 in TNBC

Filipa Lynce, MD; Rita Nanda, MD

Cross-Disease Integration of Immunotherapy Innovations

Cross-Disease Integration of Immunotherapy Innovations

Ghassan Abou-Alfa, MD, MBA; Laura Williams Goff, MD, MSCI, MMHC, FASCO; Arndt Vogel, MD, PhD

PER Resource Center: Integrating Novel Approaches in TNBC – New Avenues for TROP2-Targeting ADCs and Beyond – Nursing

PER Resource Center: Integrating Novel Approaches in TNBC – New Avenues for TROP2-Targeting ADCs and Beyond – Nursing

Aditya Bardia, MD, MPH, FASCO; Erika P. Hamilton, MD; Virginia Kaklamani, MD, DSc; Filipa Lynce, MD; Rita Nanda, MD; Tiffany A. Traina, MD, FASCO

Medical Crossfire® in Adjunctive Testing: Charting a New Course in Prostate Cancer Risk Assessment

Medical Crossfire® in Adjunctive Testing: Charting a New Course in Prostate Cancer Risk Assessment

Jason Hafron, MD; Aaron D. Berger, MD; Arpeet Shah, MD

Community Practice Connections™: Enhancing Melanoma Outcomes With Intratumoral Oncolytic Immunotherapy–Strategies for the Multidisciplinary Team

Community Practice Connections™: Enhancing Melanoma Outcomes With Intratumoral Oncolytic Immunotherapy–Strategies for the Multidisciplinary Team

Yana G. Najjar, MD; Sapna Patel, MD

Community Practice Connections™: Optimizing SCLC Treatment Strategies and Managing Adverse Events Across Disease Stages

Community Practice Connections™: Optimizing SCLC Treatment Strategies and Managing Adverse Events Across Disease Stages

Erminia Massarelli, MD, PhD, MS; Misty D. Shields, MD, PhD

Navigating the Adverse Event Landscape in HER2+ GEA Therapy

Navigating the Adverse Event Landscape in HER2+ GEA Therapy

Rahul Gosain, MD, MBA; Rohit Gosain, MD; Geoffery Ku, MD; Shruti Patel, MD

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When Are TKIs Too Aggressive for a Patient With Renal Cell Carcinoma?

Linking Patient Experience With Next Steps in Renal Cell Carcinoma

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JSKN003 Given FDA Breakthrough Therapy Status in HER2+ PROC