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Opinion|Videos|March 17, 2025

Managing Toxicity in Later-Line HER2+ mBC Treatments: Real-World Insights and Mitigation Strategies for Optimal Patient QOLs

Author(s)Ruta Rao, MD, Nilam Patel, PA-C, Joyce O’Shaughnessy, MD

Experts discuss the patient case of Janet, a 58-year-old with her 2 positive metastatic breast cancer, and after 14 months on the Cleopatra regimen with taxane, Trastuzumab, and Pertuzumab, and 11 months on Tdxd. As her disease is now progressing, so she needs 3rd line treatment. But despite some fatigue, she remains active with work and Yoga and her brain, MRIs are clear.

Episodes in this series

EP. 1 Treatment Selection and Sequencing in Third Line Settings and Beyond

EP. 1 Treatment Selection and Sequencing in Third Line Settings and Beyond

EP. 2 Janet's Journey: Navigating HER2+ Metastatic Breast Cancer & Treatment Options

EP. 2 Janet's Journey: Navigating HER2+ Metastatic Breast Cancer & Treatment Options

5 experts in this video

EP. 3 Managing Toxicity in Later-Line HER2+ mBC Treatments: Real-World Insights and Mitigation Strategies for Optimal Patient QOLs

5 experts in this video

EP. 4 Supporting HER2+ mBC Patients in Later Lines: AE Management and the Role of the Multidisciplinary Team

5 experts in this video

EP. 5 Treatment Goals, Side Effects, and Supportive Care Strategies for Patients and Caregivers with HER2+ BC

5 experts in this video

EP. 6 Barbara's Story: Navigating HER2+ MBC with Brain Metastases & Tucatinib-Based Treatment in the Second-Line Setting

5 experts in this video

EP. 7 Evolving Treatment Strategies in Early HER2+ Breast Cancer

5 experts in this video

EP. 8 Emerging First-Line Clinical Trials in HER2+ mBC: Insights from HER2CLIMB05, INAVO122, and Other Trials Advancing Precision Medicine

5 experts in this video

EP. 9 Managing Early HER2+ mBC: Patient-Centered Approaches and Evolving Treatment Strategies

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