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Opinion|Videos|March 24, 2025

Supporting HER2+ mBC Patients in Later Lines: AE Management and the Role of the Multidisciplinary Team

Author(s)Ruta Rao, MD, Nilam Patel, PA-C, Joyce O’Shaughnessy, MD

Experts discuss treatment options for HER2-positive metastatic breast cancer following progression on trastuzumab deruxtecan (T-DXd), weighing real-world data on tucatinib-capecitabine-trastuzumab versus T-DM1, considering factors such as resistance mechanisms, administration preferences, and side effect management.

Episodes in this series

EP. 1 Treatment Selection and Sequencing in Third Line Settings and Beyond

EP. 1 Treatment Selection and Sequencing in Third Line Settings and Beyond

EP. 2 Janet's Journey: Navigating HER2+ Metastatic Breast Cancer & Treatment Options

EP. 2 Janet's Journey: Navigating HER2+ Metastatic Breast Cancer & Treatment Options

5 experts in this video

EP. 3 Managing Toxicity in Later-Line HER2+ mBC Treatments: Real-World Insights and Mitigation Strategies for Optimal Patient QOLs

5 experts in this video

EP. 4 Supporting HER2+ mBC Patients in Later Lines: AE Management and the Role of the Multidisciplinary Team

5 experts in this video

EP. 5 Treatment Goals, Side Effects, and Supportive Care Strategies for Patients and Caregivers with HER2+ BC

5 experts in this video

EP. 6 Barbara's Story: Navigating HER2+ MBC with Brain Metastases & Tucatinib-Based Treatment in the Second-Line Setting

5 experts in this video

EP. 7 Evolving Treatment Strategies in Early HER2+ Breast Cancer

5 experts in this video

EP. 8 Emerging First-Line Clinical Trials in HER2+ mBC: Insights from HER2CLIMB05, INAVO122, and Other Trials Advancing Precision Medicine

5 experts in this video

EP. 9 Managing Early HER2+ mBC: Patient-Centered Approaches and Evolving Treatment Strategies

Video content above is prompted by the following:

What real world data following the use of Tucatinib and T-DXd that can help assist medical professionals.

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Knowledge is power. Don’t miss the most recent breakthroughs in cancer care.

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