Breast Cancer

Rowan Chlebowski, MD, PhD, discusses how losing 5 pounds, as seen in the Women's Intervention Nutrition Study, had a positive impact for breast cancer patients, especially whose disease was triple-negative.

Results of a large retrospective study of more than 20,000 women treated for early-stage breast cancer are shedding light on how much treatment may be too much for these early-stage cancers.

As one of the most significant predictors of hereditary breast and ovarian cancer, the BRCA1/2 genes have become the poster child for genetic testing. In the past 18 months, the floodgates for testing options have opened, as companies seek to enter the diagnostic market in the wake of the US Supreme Court's June 2013 ruling that "naturally occurring" human genes are a "product of nature" and cannot be patented, breaking Myriad Genetics' monopoly on BRCA1/2 gene testing.

Anees B. Chagpar, MD, MSc, MA, MPH, associate professor of surgery (oncology), director, The Breast Center at Smilow Cancer Hospital at Yale-New Haven, program director, Interdisciplinary Breast Fellowship, assistant director, Diversity and Health Equity at Yale Cancer Center, discusses a study that looked at patient perceptions of the impact of genetic testing for breast cancer risk on health insurance.

Jack Cuzick, PhD, a professor of epidemiology at Wolfson Institute of Preventive Medicine, discusses the side effects of tamoxifen that cause anxiety for patients.

Jean Weigert, MD, head of breast imaging for the Hospital of Central Connecticut, discusses the benefits of screening women who had normal mammograms but dense breasts.

New research has found that the overall survival of male patients with breast cancer has improved over time, but the improvement is not as good as it has been for female patients with breast cancer

New research presented at the 2014 San Antonio Breast Cancer Symposium has shown that women with triple-negative breast cancer (TNBC) are more likely to seek out information about their specific subtype and experience more fear, anxiety, and worry than women with other subtypes of breast cancer,

Tara Sanft, MD, assistant professor of medicine (medical oncology), medical director, Adult Survivorship, Yale Cancer Center Survivorship Clinic, discusses Yale's survivorship program, which is composed of three clinics.

Findings from a long-term analysis of the Women's Intervention Nutrition Study (WINS) show that the deaths of women with hormone receptor–negative breast cancers were reduced by up to 54% when they followed a program to reduce their dietary fat intake, which could provide benefit for patients with triple-negative breast cancer.

Erin W. Hofstatter, MD, assistant professor of medicine (medical oncology), co-director, Genetic Counseling Program, Yale Cancer Center, discusses a study to determine if perceived personal breast cancer risk was associated with adherence to healthy lifestyle habit.

Five years of tamoxifen continues to offer protection against breast cancer, reducing the risk of breast cancer by 29% in otherwise healthy women at high risk of the disease who have been followed now for 16 to 22 years.

Despite research findings that toxicities outweigh benefits when women over the age of 70 are treated with radiation for their early-stage breast cancer, the treatment remains commonplace 10 years later, a new study has found.

An increasing focus in oncology care is on survivorship and quality-of-life issues that arise once patients are living beyond treatment. For female breast cancer patients, important survivorship issues include sexual and reproductive health.

A group of researchers looking to better equip patients to be self-managers of their cancer have developed a new tool to help patients communicate their treatment goals more effectively.

A genomic test (also called a genomic assay) analyzes the activity of a group of genes linked to the risk of a particular disease.

Jessica Goldberg, MSN, adult gerontology nurse practitioner, fellow in palliative medicine, Memorial Sloan Kettering Cancer Center, discusses a study on creating a successful cancer self-management intervention for patients with breast cancer.

The poly (ADP-ribose) polymerase (PARP) inhibitor veliparib exhibits antitumor activity and is safe and tolerable on a continuous dosing schedule when used for the treatment of patients with BRCA-positive and BRCA–wild type tumors.

Talk with almost any breast cancer survivor, and they're likely to bring up the topic of "chemobrain," that fuzzy, murky state that patients blame for impaired memory.

Researchers have identified a new way to boost the enrollment of Latina patients with breast cancer in clinical trials via a culturally sensitive video, a tailored booklet, and the help of a patient navigator.

A systematic review of published results from 203 randomized clinical trials, involving more than 80 different integrative therapies, has yielded evidence-based recommendations for clinicians and their patients with breast cancer about which of these therapies may be most helpful to manage their symptoms.

In May 2014, ASCO issued guidelines recommending the administration of adjuvant tamoxifen for 10 years in women with stage I-III hormone receptor (HR)-positive breast cancer, based on data from the collection of 5 clinical trials.

October 13 was National Metastatic Breast Cancer Awareness Day. Managing Editor Claire Nixon talks with oncology counselor Sage Bolte, Ph.D., about how to deal with October's pink onslaught if you're living with metastasis and Breastcancer.org Medical Adviser Brian Wojciechowski, M.D., on where we are today with metastatic treatment options.

New research has identified a genetic variant that helps reduce the risk of breast cancer in some Latina patients by 40% to 80%.

Even though breast cancer predominantly affects white women, breast cancer outcomes are worse among black women. But a new study suggests that enrollment in a federal program may help reduce racial disparities among these patients.

Only 10% of breast cancer is hereditary. Which means 90% is not. Now, you can't change your genes, but healthier lifestyle choices can make a difference.

A new study has found that nearly one third of cancer patients suffer from anxiety or other mental health challenges, with breast cancer patients, head and neck cancer patients and melanoma patients suffering the most.

New research suggests that exposure to dim light at night may cause breast cancer patients to become resistant to certain types of therapy.

Many studies have found a link between regular exercise and a lower risk of being diagnosed with breast cancer or breast cancer coming back (recurrence). As a result, the American Cancer Society and many doctors recommend that women who've been diagnosed with breast cancer, as well as those who haven't, exercise regularly – about 4 to 5 hours per week at a moderate intensity level. (Brisk walking is considered moderate intensity exercise.)

To address the question of whether axillary dissection is necessary in older women, researchers in Milan, Italy recruited 238 women aged 65-80 years with cT1cN0 breast cancer and randomized them to receive conservative surgery with or without axillary node dissection.