Becoming Familiar With Patients’ AEs is Essential, Says Expert
Axel Stuart Merseburger, MD, PhD, explained that with TKIs like axitinib, it is necessary for oncology nurses to spend time with each patient to provide the best care.
Real-World Data Back First-Line Avelumab and Axitinib in Advanced RCC
Avelumab in combination with axitinib was found effective and safe as frontline treatment for advanced RCC in real-world findings.
NCCN Guideline Updates on ctDNA Stance in MCC and Colon, Rectal Cancer
The NCCN updated its guidelines to clarify the role of ctDNA as a biomarker for recurrence risk in colon and rectal cancer and for disease monitoring in Merkel cell carcinoma.
Tivozanib Combo Yields Similar PROs to Monotherapy in Advanced Clear Cell RCC
Patient-reported outcomes were consistent between patients with RCC using tivozanib/nivolumab and tivozanib monotherapy according to study findings.
Utilizing Resources to Educate Oncology Nurses, APPs on Latest Advances in Breast Cancer
Erica S. Doubleday, MS, FNP-C, BSN, RN, discussed taking advantage of available resources to provide comprehensive care for patients with breast cancer.
Dose Reductions Possible for Tivozanib With and Without Nivolumab for RCC
Katy Beckermann, MD, PhD, explained that oncology nurses and APPs should be ready to administer and explain dose modifications for patients with RCC.
T-DM1 Further Improves DFS and OS vs Trastuzumab in HER2-Positive Early Breast Cancer
T-DM1 reduced risk of invasive disease events and death compared with trastuzumab in HER2-positive early breast cancer with residual invasive disease after neoadjuvant therapy.
Nivolumab Combo for RCC Necessitates AE Monitoring, Awareness
According to Laurence Albiges, MD, PhD, treatment of RCC with cabozantinib, nivolumab, and ipilimumab can cause potentially serious toxicities that should be closely monitored.
Immune Checkpoint Inhibitors May Increase Psoriasis Risk in Patients With Cancer
Immune checkpoint inhibitors for patients with cancer may be associated with an increased risk for psoriasis when compared with chemotherapy, monoclonal antibodies, and protease inhibitors.
Oncology Nurses and APPs Are More Than a ‘Bystander’ in Clinical Trials
The role of oncology nurses and APPs in research is largely to stay abreast of trials that may be useful to patients and recommend them whenever possible, according to Erica Doubleday, MS, FNP-C, BSN, RN.
Proactive Onco-Coaching Linked to Higher OS in mRCC
Proactive onco-coaching did not improve QOL but was associated with improved OS in patients with metastatic renal cell carcinoma receiving TKIs and ICIs.
Olanzapine May Address AEs From TKIs for Kidney and Other Cancers
Patients treated with tyrosine kinase inhibitors received olanzapine to address adverse effects including nausea/vomiting, anorexia, insomnia, and weight loss.
KN026-Docetaxel Combo Shows Efficacy, Safety in HER2+ Metastatic Breast Cancer
Patients with recurrent/metastatic HER2-positive breast cancer experienced durable response and manageable safety from KN026-docetaxel combination therapy.
Positive Responses to Liso-Cel Observed in Relapsed/Refractory Marginal Zone Lymphoma
Lisocabtagene maraleucel demonstrated a statistically significant overall response rate in adults with relapsed/refractory marginal zone lymphoma.
Cabozantinib Combo Maintains PFS for Advanced RCC at Follow-Up
New results uphold previous findings regarding the efficacy of cabozantinib, nivolumab, and ipilumumab arm for advanced renal cell carcinoma.
Nivolumab Plus Cabozantinib Effective Long-Term for Advanced RCC
Patients with advanced RCC who were treated with nivolumab plus cabozantinib had a median PFS of 16.4 months compared with 8.3 months from sunitinib alone.
High PSA Levels Before HIFU May Increase Recurrence Risk in Intermediate-Risk Prostate Cancer
Men with intermediate-risk prostate cancer and high PSA levels before HIFU treatment had a greater risk of both overall recurrence and treatment failure.
Enfortumab Vedotin and Pembrolizumab Effective in Treating Primary UTUC Lesions
Enfortumab vedotin alone and in combination with pembrolizumab showed promise in patients with upper tract urothelial carcinoma, particularly those ineligible for standard chemotherapy.
Real-World Data Support Enfortumab Vedotin for Urothelial Carcinoma Treatment
Real-world data demonstrate significant outcome improvements with enfortumab vedotin in patients with unresectable or metastatic urothelial carcinoma.
Darolutamide-ADT Combination Lengthens rPFS in mHSPC Regardless of Disease Volume
Patients with metastatic hormone-sensitive prostate cancer experienced increase rPFS and other efficacy end points with darolutamide plus ADT.
Certain AEs May Indicate Improved PFS With Enfortumab Vedotin for Urothelial Carcinoma
Improved progression-free survival in metastatic urothelial carcinoma was observed in patients experiencing neuropathy, skin rash, and hyperglycemia following enfortumab vedotin.
Benefits, Risks With EBRT Plus SADT in Intermediate-Risk Prostate Cancer
Increase in QOL and decrease in sexual function are among the benefits and risks, respectively, of adding SADT to EBRT for intermediate-risk prostate cancer.
Enfortumab Vedotin May Be Safe in Ultra-Elderly Patients With Urothelial Carcinoma
Findings also suggested that an up-front dose reduction of enfortumab vedotin may benefit older patients with urothelial carcinoma.
Digital Health Tool Helps Patients With Prostate Cancer During Consultations
MyCareGorithm was met with high approval from patients, companions, and physicians, with all 3 groups reporting they’d recommend the tool to other patients.
ARASENS Trial: G-CSF Enables Full Docetaxel Dose in mHSPC
While lower relative dose intensity of docetaxel was associated with higher rates of G-CSF use and more adverse events, discontinuation rates were low across all groups.
177Lu-PSMA-617 With Enzalutamide for mCRPC Boosts OS, QOL
Patients with mCRPC taking LuPSMA had a median OS of 34 months vs 26 months with enzalutamide alone.
Clinical Practice Gaps Persist in Biomarker Testing for mCRPC Management
With delays in biomarker testing and treatment for metastatic castration-resistant prostate cancer, continued education is needed to address these gaps.
With Personalized Cancer Vaccines On the Horizon, What Is Nurses’ Role?
Nurses and APPs provide an essential link between physicians and patients when facilitating and monitoring outcomes with personalized cancer vaccines.
Talazoparib-Enzalutamide Combo Increases OS in mCRPC
Patients with HRR-deficient metastatic castration-resistant prostate cancer saw a 14-month boost in OS and a 38% lower risk of death with talazoparib plus enzalutamide.
Amezalpat Receives FDA Fast Track Designation for Hepatocellular Carcinoma
Amezalpat has been granted FDA fast track designation as treatment for patients with hepatocellular carcinoma.
Nurses Lead Toxicity Monitoring in Indolent Lymphoma Care
Osimertinib/Chemo Boosts Survival in Frontline EGFR+ NSCLC
Lutetium Lu 177 Dotatate Brings Partial Response in Metastatic BP-NETs
Safety Management With Amivantamab Plus Lazertinib in NSCLC