Olanzapine Significantly Reduces CINV in Patients Receiving MEC
A phase 3 trial based out of India suggests that olanzapine may be useful in reducing chemotherapy-induced nausea and vomiting.
FDA Revisits Pembrolizumab’s Gastric Cancer Indication
The FDA has restricted the indication for gastric cancer to only include patients whose tumors express PD-L1 (CPS ≥ 1) as determined by an FDA-approved test.
Trilaciclib Snags ASCO Recommendation in Extensive-Stage Small Cell Lung Cancer
New ASCO guidelines recommend trilaciclib for patients with untreated or previously treated extensive-stage small cell lung cancer who are receiving chemotherapy or chemoimmunotherapy.
FDA Launches Priority Review of Liso-Cel in Pretreated CLL/SLL
Lisocabtagene maraleucel is under consideration as a potential treatment option for patients with chronic lymphocytic leukemia or small lymphocytic lymphoma.
Up-Front Advance Care Planning May Lead to Better End-of-Life Outcomes in Cancer Care
Patients who were in the intervention arm were 67% less likely to go to the emergency department in the last days of their life.
Atezolizumab Combo Reduces Risk of Death by 32% Over Bevacizumab/Chemo in Recurrent Cervical Cancer
The median OS achieved with atezolizumab plus bevacizumab and chemotherapy was 32.1 months vs 22.8 months with bevacizumab and chemotherapy alone.
'Undiagnosed Cancer Clinic’ Helps Improve Cancer Care Accessibility
The Undiagnosed Cancer Clinic, or UCC, was established with the goal of reducing the time that patients wait for their initial oncology consultation appointments.
FDA Approves Fruquintinib for Patients With Pretreated Metastatic Colorectal Cancer
The FDA has approved fruquintinib to treat adults with metastatic colorectal cancer.
High Price Tags and Implications: Cost of Care Is an Important Conversation in Cancer
Screening for financial toxicity should be routine in cancer care, according to investigators.
Reimagining Frailty Screenings in Head and Neck Cancer
Incorporating frailty screenings into preexisting workflows may be an effective way to provide more holistic care to patients with head and neck cancer.
Screening for Pain and Depression is Not Enough in Cancer Care
Investigators reflect on the Oncology Care Model and its implications.
Niraparib-Based Triplet Therapy Offers OS Advantage in BRCA1/2+ mCRPC
The median overall survival with niraparib, abiraterone acetate, and prednisone was 30.4 months vs 28.6 months with abiraterone acetate and prednisone alone.
Lenvatinib/Pembrolizumab Generates Lasting Responses in Advanced Kidney Cancer
The duration of response was 39.2 months among patients with 1 metastatic site treated in the combination arm vs 29.5 months for patients given sunitinib.
Phase 3 KEYNOTE-564 Meets it Secondary Endpoint in RCC
Adjuvant pembrolizumab improved overall survival vs placebo in patients with renal cell carcinoma at intermediate-high or high risk of recurrence.
Ibrutinib Maintenance Therapy Shows Benefit in MCL Following Induction Therapy
The 3-year progression-free survival rate was 94% and the 3-year overall survival rate was 97%.
Oncology Nurses Are Uniquely Qualified to Meet the Needs of Patients With Lung Cancer
As with all patients with cancer, providing care for those with lung cancer involves both physiological and psychological aspects.
Cabozantinib Lengthens PFS in Pretreated Patients With Neuroendocrine Tumors
The median progression-free survival with cabozantinib was 8.3 months vs 3.2 months with placebo among patients with extra-pancreatic neuroendocrine tumors.
Delivering Teclistamab in the Outpatient Setting
Freshta Poupal, RN, and Frannie Bell, NP, share their experiences with teclistamab in clinical practice.
How I Counsel Patients About Lung Cancer Screening
A lung cancer screening navigator offers their perspective on shared decision-making.
Innovative Project Reduces Operating–Room-Related Pressure Injuries by 50.5%
An initiative led by nurses helped reduce operating-room pressure injuries and saved their institution an estimated $80,210 per year.
FDA Grants Pembrolizumab New Biliary Tract Cancer Indication
The FDA has approved pembrolizumab in combination with chemotherapy as a treatment for patients with locally advanced unresectable or metastatic biliary tract cancer.
ctDNA Monitoring is a Piece of the Puzzle in CRC Treatment
Holly Chitwood, DNP, FNP-C, AGACNP-BC, explains how circulating tumor DNA monitoring helps providers screen minimal residual disease in individuals with colorectal cancer.
Oncology Care Model: What Did We Learn?
The Oncology Care Model did not significantly improve care, yet patients were satisfied with their care and many oncologists overcame their hesitancy towards value-based models.
FDA Approves Toripalimab Regimens to Treat Adults With Nasopharyngeal Carcinoma
The FDA has approved toripalimab, with cisplatin and gemcitabine, and as a monotherapy, to treat adults with nasopharyngeal carcinoma.
Amivantamab/Chemo Elicits Responses in EGFR NSCLC That Has Progressed On Osimertinib
Patients who received amivantamab plus lazertinib and chemotherapy achieved a median progression-free survival of 8.3 months.
Frontline Atezolizumab/Chemo Shows PFS Benefit in Advanced/Recurrent Endometrial Cancer
The median progression-free survival was not reached with atezolizumab plus chemotherapy vs 6.9 months in the placebo group of patients with advanced or recurrent endometrial cancer.
Managing Early Satiety in MPNs
Amanda Smith, a registered nurse with Huntsman Cancer Institute, discusses the impact that early satiety can have on patients with myeloproliferative neoplasms and the role nurses play in helping patients manage this symptom.
Phase 3 Trial Supports Amivantamab Plus Lazertinib Over Osimertinib in Advanced EGFR+ NSCLC
The median progression-free survival was 23.7 months with the combination vs 16.6 months with osimertinib alone.
177Lu-PSMA-617 Improves rPFS in Metastatic Castration-Resistant Prostate Cancer
The median radiologic progression-free survival was 12.02 months in the 177Lu-PSMA-617 group vs 5.59 months in the androgen receptor pathway inhibitor change group.
Certain Patients With Advanced/Metastatic NSCLC Derive PFS Benefit With Dato-DXd
Datopotamab deruxtecan improved progression-free survival in select subsets of patients with advanced or metastatic non–small-cell lung cancer.
Relacorilant/Nab-Paclitaxel Is Convenient, Safe in Ovarian Cancer
Neoadjuvant Nivolumab Regimen Improves OS in Resectable NSCLC
Relacorilant Combo Boosts PFS in Resistant Ovarian Cancer
Nivolumab/Ipilimumab To Be New MSI-H/dMMR mCRC Standard of Care