Are there any serious AEs of note that worry you? Which AEs have the biggest impact on a patient’s quality of life?
How do you balance symptom management with maintaining treatment efficacy?
What has been your experience with the incidence and management of GI adverse events? Fatigue?
How do these compare to AEs associated with other similar therapies.
How do you handle dose modifications or treatment interruptions due to adverse events?
Do you find does modifications impact patient outcomes?
When might you consider stopping treatment
Can you share any tips for working together as a multidisciplinary care team to ensure the most effective management of AEs associated with KRAS targeted therapies?
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