Lorlatinib AE Management: Weight Gain and GI Issues

Opinion
Video

An expert discussion surrounding experience with managing weight gain and gastrointestinal adverse events associated with lorlatinib, addressing quality of life, symptom mitigation strategies, and maintaining treatment efficacy.

Video content above is prompted by the following:

  • What has been your experience with the incidence and management of weight gain that some patients experience when taking lorlatinib?
    • How do you discuss the impact of this symptom on QOL vs the benefit of treatment?
    • How do you balance symptom management with maintaining treatment efficacy?
  • What has been your experience with the incidence and management of GI adverse events associated with lorlatinib?
    • Do you have any prophylactic tips for patients to mitigate GI issues?
    • How does this compare to other ALK inhibitors?
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