
News|Articles|August 19, 2026
What Nurses Need to Know About FDA-Approved Iberdomide in Multiple Myeloma
Author(s)By ONN Staff
Fact checked by: Alex Biese
Oncology clinical trial nurse navigator Elise Curry, RN, breaks down the key clinical questions surrounding the FDA approval of oral iberdomide.
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The FDA granted accelerated approval to iberdomide (Zenbexus, Bristol-Myers Squibb Company) combined with daratumumab and hyaluronidase-fihj and dexamethasone for adults with relapsed or refractory multiple myeloma (RRMM) who received at least one prior line of therapy, including a proteasome inhibitor and an immunomodulatory agent. This approval introduces the first approved cereblon E3 ligase modulator (CELMoD) agent, establishing a novel therapeutic class in the myeloma landscape.
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