
Tyrosine-kinase inhibitors (TKIs) are a mainstay of therapy for patients with advanced thyroid cancer, more than doubling progression-free survival. Unfortunately, their use is limited not only by gastrointestinal adverse events (AEs), such as diarrhea and anorexia, but also by significant weight loss, which has been reported in 10% to 50% of patients treated with TKI therapies.





















