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Opinion|Videos|March 28, 2025

Managing Symptoms and Quality of Life During HER2-Targeted Therapy for Upper GI Cancer

Author(s)David Zhen, MD, Nataliya Uboha, MD, Samuel Cytryn, MD

Experts discuss how to manage fatigue, abdominal pain, and other treatment-related symptoms to maintain or improve quality of life for patients undergoing HER2-targeted therapy and share strategies for supporting patients with declining performance status (eg, ECOG performance status [PS] 2) in balancing treatment efficacy with daily functioning.

Episodes in this series

EP. 1 Navigating Immune-Related Adverse Events With Nivolumab in Upper GI Cancer

EP. 1 Navigating Immune-Related Adverse Events With Nivolumab in Upper GI Cancer

EP. 2 Robert’s Journey With HER2- Upper GI Cancer

EP. 2 Robert’s Journey With HER2- Upper GI Cancer

EP. 3 Strategies for Managing FOLFOX Toxicity in Upper GI Cancer

EP. 3 Strategies for Managing FOLFOX Toxicity in Upper GI Cancer

EP. 4 Supporting Patients Through Treatment for Upper GI Cancer Care

EP. 4 Supporting Patients Through Treatment for Upper GI Cancer Care

EP. 5 Communicating Treatment Adverse Effects: Strategies for Managing Expectations During Treatment for Upper GI Cancer

EP. 5 Communicating Treatment Adverse Effects: Strategies for Managing Expectations During Treatment for Upper GI Cancer

EP. 6 Balancing Treatment Intensity and Quality of Life in Upper GI Cancer

EP. 6 Balancing Treatment Intensity and Quality of Life in Upper GI Cancer

EP. 7 Megan’s Journey With HER2+ Upper GI Cancer

EP. 7 Megan’s Journey With HER2+ Upper GI Cancer

EP. 8 Managing Adverse Events With Trastuzumab Deruxtecan: Early Detection and ILD Monitoring Strategies

EP. 8 Managing Adverse Events With Trastuzumab Deruxtecan: Early Detection and ILD Monitoring Strategies

EP. 9 Managing Symptoms and Quality of Life During HER2-Targeted Therapy for Upper GI Cancer

EP. 9 Managing Symptoms and Quality of Life During HER2-Targeted Therapy for Upper GI Cancer

EP. 10 Multidisciplinary Collaboration in Managing Treatment-Related AEs in Upper GI Cancer

EP. 10 Multidisciplinary Collaboration in Managing Treatment-Related AEs in Upper GI Cancer

EP. 11 Bridging Communication Gaps: Comprehensive Care for Upper GI Cancer Treatment

EP. 11 Bridging Communication Gaps: Comprehensive Care for Upper GI Cancer Treatment

Video content above is prompted by the following:

• How do you manage fatigue, abdominal pain, and other treatment-related symptoms to maintain or improve quality of life for patients undergoing HER2-targeted therapy?
• What strategies do you use to support patients with declining performance status (eg, ECOG PS 2) in balancing treatment efficacy with daily functioning ?

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