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Opinion|Videos|February 26, 2025

Navigating Immune-Related Adverse Events With Nivolumab in Upper GI Cancer

Author(s)David Zhen, MD, Nataliya Uboha, MD, Samuel Cytryn, MD

Experts discuss key immune-related adverse events (irAEs) to monitor in patients receiving nivolumab, how to differentiate these from disease-related symptoms, and how to manage moderate to severe irAEs, including factors that determine whether immunotherapy should be paused or discontinued.

Episodes in this series

EP. 1 Navigating Immune-Related Adverse Events With Nivolumab in Upper GI Cancer

EP. 1 Navigating Immune-Related Adverse Events With Nivolumab in Upper GI Cancer

EP. 2 Robert’s Journey With HER2- Upper GI Cancer

EP. 2 Robert’s Journey With HER2- Upper GI Cancer

EP. 3 Strategies for Managing FOLFOX Toxicity in Upper GI Cancer

EP. 3 Strategies for Managing FOLFOX Toxicity in Upper GI Cancer

EP. 4 Supporting Patients Through Treatment for Upper GI Cancer Care

EP. 4 Supporting Patients Through Treatment for Upper GI Cancer Care

EP. 5 Communicating Treatment Adverse Effects: Strategies for Managing Expectations During Treatment for Upper GI Cancer

EP. 5 Communicating Treatment Adverse Effects: Strategies for Managing Expectations During Treatment for Upper GI Cancer

EP. 6 Balancing Treatment Intensity and Quality of Life in Upper GI Cancer

EP. 6 Balancing Treatment Intensity and Quality of Life in Upper GI Cancer

EP. 7 Megan’s Journey With HER2+ Upper GI Cancer

EP. 7 Megan’s Journey With HER2+ Upper GI Cancer

EP. 8 Managing Adverse Events With Trastuzumab Deruxtecan: Early Detection and ILD Monitoring Strategies

EP. 8 Managing Adverse Events With Trastuzumab Deruxtecan: Early Detection and ILD Monitoring Strategies

EP. 9 Managing Symptoms and Quality of Life During HER2-Targeted Therapy for Upper GI Cancer

EP. 9 Managing Symptoms and Quality of Life During HER2-Targeted Therapy for Upper GI Cancer

EP. 10 Multidisciplinary Collaboration in Managing Treatment-Related AEs in Upper GI Cancer

EP. 10 Multidisciplinary Collaboration in Managing Treatment-Related AEs in Upper GI Cancer

EP. 11 Bridging Communication Gaps: Comprehensive Care for Upper GI Cancer Treatment

EP. 11 Bridging Communication Gaps: Comprehensive Care for Upper GI Cancer Treatment

Video content above is prompted by the following:

• What are the key irAEs to monitor in patients receiving nivolumab, and how do you differentiate these from disease-related symptoms ?

• How do you approach the management of moderate to severe irAEs, and what factors determine whether immunotherapy should be paused or discontinued?

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